Hyper-responsive Toll-like receptor 7 and 9 activation in NADPH oxidase-deficient B lymphoblasts

Keyphrases

• Autoreactivity 20%
• B Cell Lines 20%
• B Cells 100%
• B Lymphoblasts 100%
• Chronic Granulomatous Disease 60%
• Congenital Immunodeficiency 20%
• Cytokine Secretion 20%
• Endosomal 20%
• Gene-deficient Mice 20%
• HyPer 100%
• Kinase Activation 20%
• Leukocytes 20%
• Multisubunit 20%
• NADPH Oxidase 100%
• Nucleic Acids 20%
• Oxidase 100%
• Oxidase Activity 20%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 20%
• P40phox 20%
• P47phox 20%
• Patient-derived 20%
• Phagocytic Cells 20%
• Reactive Oxygen Species 40%
• Receptor Signaling 20%
• Single Guide RNA (sgRNA) 20%
• Toll-like 100%
• Toll-like Receptor 7 (TLR7) 60%
• Toll-like Receptor 9 (TLR9) 20%
• β-cell Function 20%

Biochemistry, Genetics and Molecular Biology

• B Cell 100%
• Cell Function 14%
• Cytokine Release 14%
• Infectious Agent 14%
• Leukocyte 14%
• Lymphoblast 100%
• Messenger RNA 14%
• Myeloid 14%
• NAD(P)H Oxidase 100%
• Nucleic Acid 14%
• Oxidase 85%
• Oxidoreductase 85%
• P38 Mitogen-Activated Protein Kinases 14%
• Phagocyte 14%
• RNA 14%
• TLR7 42%
• TLR9 14%
• Toll-Like Receptor 100%

Immunology and Microbiology

• B Cell 100%
• B Lymphoblast 100%
• Cell Function 14%
• Cell Line 14%
• Chronic Granulomatous Disease 42%
• Cytokine Release 14%
• Immunodeficiency 14%
• Infectious Agent 14%
• Leukocyte 14%
• Mitogen 14%
• Myeloid 14%
• NADPH Oxidase 100%
• Phagocyte 14%
• TLR7 42%
• TLR9 14%
• Toll-Like Receptor 100%