Hydrophobic adsorption chromatography of colony-stimulating activities and erythroid-enhancing activity from the human monocyte-like cell line, GCT

C. N. Abboud, J. K. Brennan, G. H. Barlow, M. A. Lichtman

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

The human cell line, GCT, secretes hemopoietins into serum-free culture medium. The conditioned medium contains activities that stimulate neutrophil-monocyte, macrophage, eosinophil, and erythroid colony growth in human marrow cultures. We have used hydrophobic adsorption chromatography to separate a neutrophil-monocyte colony-stimulating activities. This hydrophobic CSF has no eosinophil-stimulating activity and is virtually devoid of erythroid-stimulating activity.

Original languageEnglish
Pages (from-to)1148-1154
Number of pages7
JournalBlood
Volume58
Issue number6
DOIs
StatePublished - 1981

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