Hydrocephalus: A previously unrecognized predictor of poor outcome from supratentorial intracerebral hemorrhage

Research output: Contribution to journalArticle

240 Scopus citations

Abstract

Background and Purpose - Although several factors have been identified that predict outcome after intracerebral hemorrhage (ICH), no previous study has investigated the impact of hydrocephalus. The purpose of this study was to determine whether the presence of hydrocephalus after ICH would predict mortality and functional outcome. Methods - Patients with spontaneous supratentorial ICH were identified in our prospectively collected database to determine the following: age, sex, race, past medical history; Glasgow Coma Scale (GCS) score and blood pressure on admission; use of mechanical ventilation, mannitol, and ventriculostomy; and medical complications. CT scans performed within 24 hours of hemorrhage were retrospectively analyzed to determine lesion size and location, pineal shift, cisternal effacement, intraventricular hemorrhage (IVH), and hydrocephalus. Outcome was determined with use of hospital disposition (dead, nursing home, rehabilitation, home) and functional outcome (Functional Independence Measure [FIM]) at 3 months. Patients with and without hydrocephalus were compared and univariate and multivariate analyses performed to determine whether hydrocephalus was an independent predictor of mortality. Data are presented as mean±SD. Results - Of the 81 patients studied, 40 had hydrocephalus. Those with hydrocephalus were younger (57 ± 15 versus 67 ± 15 years), had lower GCS scores (8.2±4.2 versus 11±2.9), were more likely to have ganglionic or thalamic hemorrhages, and were intubated more frequently (70% versus 27%). Hospital mortality was higher in patients with hydrocephalus (51% versus 2%), and fewer patients went home (21% versus 35%). Those who died had higher hydrocephalus scores (9.67±7.1 versus 5.75±4.5). Outcome was no different if a ventriculostomy was placed. The final logistic regression model included hydrocephalus score, gender, GCS, and pineal shift, and it correctly predicted 85% of patients as dead or alive. Multivariate analyses indicated that hydrocephalus is an independent predictor of mortality. Conclusions - We conclude that hydrocephalus is an independent predictor of mortality after ICH.

Original languageEnglish
Pages (from-to)1352-1357
Number of pages6
JournalStroke
Volume29
Issue number7
DOIs
StatePublished - Jul 1998

Keywords

  • Hydrocephalus
  • Intracerebral hemorrhage
  • Intraventricular hemorrhage
  • Stroke outcome

Fingerprint Dive into the research topics of 'Hydrocephalus: A previously unrecognized predictor of poor outcome from supratentorial intracerebral hemorrhage'. Together they form a unique fingerprint.

  • Cite this