Hybrid silica nanoparticles for multimodal imaging

William J. Rieter; Jason S. Kim; Kathryn M.L. Taylor; Hongyu An; Weili Lin; Teresa Tarrant; Wenbin Lin

doi:10.1002/anie.200604738

Hybrid silica nanoparticles for multimodal imaging

William J. Rieter, Jason S. Kim, Kathryn M.L. Taylor, Hongyu An, Weili Lin, Teresa Tarrant, Wenbin Lin

Research output: Contribution to journal › Article › peer-review

271 Scopus citations

Abstract

(Figure Presented) Lighting things up: Multifunctional silica nanoparticles containing a luminescent core and a paramagnetic coat are prepared, and their utility as multimodal imaging probes is demonstrated in vitro. Monocyte cells can be labeled with the hybrid nanoparticles with greater than 98% efficiency and do not experience measurable toxicity even at a high loading of 0.123 mg per 5000 cells.

Original language	English
Pages (from-to)	3680-3682
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	20
DOIs	https://doi.org/10.1002/anie.200604738
State	Published - 2007

Keywords

Gadolinium
Imaging agents
Magnetic resonance imaging
Nanostructures
Silicon

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10.1002/anie.200604738

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abstract = "(Figure Presented) Lighting things up: Multifunctional silica nanoparticles containing a luminescent core and a paramagnetic coat are prepared, and their utility as multimodal imaging probes is demonstrated in vitro. Monocyte cells can be labeled with the hybrid nanoparticles with greater than 98% efficiency and do not experience measurable toxicity even at a high loading of 0.123 mg per 5000 cells.",

keywords = "Gadolinium, Imaging agents, Magnetic resonance imaging, Nanostructures, Silicon",

author = "Rieter, {William J.} and Kim, {Jason S.} and Taylor, {Kathryn M.L.} and Hongyu An and Weili Lin and Teresa Tarrant and Wenbin Lin",

year = "2007",

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journal = "Angewandte Chemie - International Edition",

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AU - Rieter, William J.

AU - Kim, Jason S.

AU - Taylor, Kathryn M.L.

AU - An, Hongyu

AU - Lin, Weili

AU - Tarrant, Teresa

AU - Lin, Wenbin

PY - 2007

Y1 - 2007

N2 - (Figure Presented) Lighting things up: Multifunctional silica nanoparticles containing a luminescent core and a paramagnetic coat are prepared, and their utility as multimodal imaging probes is demonstrated in vitro. Monocyte cells can be labeled with the hybrid nanoparticles with greater than 98% efficiency and do not experience measurable toxicity even at a high loading of 0.123 mg per 5000 cells.

AB - (Figure Presented) Lighting things up: Multifunctional silica nanoparticles containing a luminescent core and a paramagnetic coat are prepared, and their utility as multimodal imaging probes is demonstrated in vitro. Monocyte cells can be labeled with the hybrid nanoparticles with greater than 98% efficiency and do not experience measurable toxicity even at a high loading of 0.123 mg per 5000 cells.

KW - Gadolinium

KW - Imaging agents

KW - Magnetic resonance imaging

KW - Nanostructures

KW - Silicon

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U2 - 10.1002/anie.200604738

DO - 10.1002/anie.200604738

M3 - Article

C2 - 17415734

AN - SCOPUS:34250830892

SN - 1433-7851

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EP - 3682

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 20

ER -

Hybrid silica nanoparticles for multimodal imaging

Abstract

Keywords

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