Hybrid reference genome assemblies for Leishmania (Viannia) braziliensis, a primary agent of mucocutaneous leishmaniasis

James A. Cotton; Frederik Van den Broeck; Peter J. Myler; Natalia S. Akopyants; Matthew Berriman; Stephen M. Beverley

doi:10.1128/mra.01317-24

Hybrid reference genome assemblies for Leishmania (Viannia) braziliensis, a primary agent of mucocutaneous leishmaniasis

James A. Cotton
, Frederik Van den Broeck
, Peter J. Myler
, Natalia S. Akopyants
, Matthew Berriman
, Stephen M. Beverley

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We report high-quality long-read genome assemblies and annotations for two widely studied reference strains of Leishmania (Viannia) braziliensis, a primary agent of cutaneous and mucocutaneous leishmaniasis. These genomes should facilitate studies of animal infectivity and pathogenesis of cutaneous and severe mucocutaneous leishmaniasis.

Original language	English
Journal	Microbiology Resource Announcements
Volume	14
Issue number	7
DOIs	https://doi.org/10.1128/mra.01317-24
State	Published - Jul 2025

Keywords

Kinetoplastida
Leishmania braziliensis
South America
Trypanosomatidae
Viannia
comparative genomics
mucocutaneous leishmaniasis

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10.1128/mra.01317-24

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title = "Hybrid reference genome assemblies for Leishmania (Viannia) braziliensis, a primary agent of mucocutaneous leishmaniasis",

abstract = "We report high-quality long-read genome assemblies and annotations for two widely studied reference strains of Leishmania (Viannia) braziliensis, a primary agent of cutaneous and mucocutaneous leishmaniasis. These genomes should facilitate studies of animal infectivity and pathogenesis of cutaneous and severe mucocutaneous leishmaniasis.",

keywords = "Kinetoplastida, Leishmania braziliensis, South America, Trypanosomatidae, Viannia, comparative genomics, mucocutaneous leishmaniasis",

author = "Cotton, \{James A.\} and \{Van den Broeck\}, Frederik and Myler, \{Peter J.\} and Akopyants, \{Natalia S.\} and Matthew Berriman and Beverley, \{Stephen M.\}",

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year = "2025",

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doi = "10.1128/mra.01317-24",

language = "English",

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journal = "Microbiology Resource Announcements",

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T1 - Hybrid reference genome assemblies for Leishmania (Viannia) braziliensis, a primary agent of mucocutaneous leishmaniasis

AU - Cotton, James A.

AU - Van den Broeck, Frederik

AU - Myler, Peter J.

AU - Akopyants, Natalia S.

AU - Berriman, Matthew

AU - Beverley, Stephen M.

PY - 2025/7

Y1 - 2025/7

N2 - We report high-quality long-read genome assemblies and annotations for two widely studied reference strains of Leishmania (Viannia) braziliensis, a primary agent of cutaneous and mucocutaneous leishmaniasis. These genomes should facilitate studies of animal infectivity and pathogenesis of cutaneous and severe mucocutaneous leishmaniasis.

AB - We report high-quality long-read genome assemblies and annotations for two widely studied reference strains of Leishmania (Viannia) braziliensis, a primary agent of cutaneous and mucocutaneous leishmaniasis. These genomes should facilitate studies of animal infectivity and pathogenesis of cutaneous and severe mucocutaneous leishmaniasis.

KW - Kinetoplastida

KW - Leishmania braziliensis

KW - South America

KW - Trypanosomatidae

KW - Viannia

KW - comparative genomics

KW - mucocutaneous leishmaniasis

UR - https://www.scopus.com/pages/publications/105010775772

U2 - 10.1128/mra.01317-24

DO - 10.1128/mra.01317-24

M3 - Article

C2 - 40525854

AN - SCOPUS:105010775772

SN - 2576-098X

VL - 14

JO - Microbiology Resource Announcements

JF - Microbiology Resource Announcements

IS - 7

ER -

Hybrid reference genome assemblies for Leishmania (Viannia) braziliensis, a primary agent of mucocutaneous leishmaniasis

Abstract

Keywords

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