Hybrid pet imaging in neurologic disease: PET/MRI rather than PET/CT

Erik S. Musiek, Lise Borgwardt, Babak Saboury, Abass Alavi

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Both structural and functional neuroimaging modalities have provided great insight into a variety of neurologic diseases. Techniques have now become available which allow coregistration of structural and functional imaging data, which have provided unique insights into neurologic function and pathophysiology. Hybrid SPECT/CT and PET/CT imaging platforms have further advanced understanding of brain structure/function. Recently, the first true hybrid PET/MRI devices have been introduced. This technologic breakthrough promises to contribute greatly to hybrid neuroimaging. Herein we review the impact of hybrid SPECT/CT and PET/CT, as well as PET/MRI coregistration techniques on a variety of neurologic diseases, including brain tumors, neurodegenerative diseases, epilepsy, cerebrovascular diseases, and pediatric conditions, with an emphasis on the future utility of hybrid PET/MRI imaging.

Original languageEnglish
Pages (from-to)193-201
Number of pages9
JournalCurrent Medical Imaging Reviews
Issue number3
StatePublished - Aug 1 2011


  • Alzheimer's disease
  • CT
  • Epilepsy
  • FDG
  • Hybrid imaging
  • MRI
  • PET
  • PET/CT
  • Parkinson's disease
  • Stroke


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