@article{b7861c0c5e774bf78d1786af06f7c0b3,
title = "Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy",
abstract = "Fox et al. demonstrate in a Huntington's disease (HD) mouse model and HD-patient-derived neurons that the autophagy adaptor protein Alfy/WDFY3 is required for removal of aggregated protein and that depletion of Alfy hastens the pathogenic onset of HD.",
keywords = "Alfy, Huntington's disease, Wdfy3, autophagy, direct conversion, mice, neurodegeneration, patient fibroblasts, proteinopathy, selective autophagy",
author = "Fox, {Leora M.} and Kiryung Kim and Johnson, {Christopher W.} and Shawei Chen and Croce, {Katherine R.} and Victor, {Matheus B.} and Evelien Eenjes and Bosco, {Joan R.} and Randolph, {Lisa K.} and Ioannis Dragatsis and Dragich, {Joanna M.} and Yoo, {Andrew S.} and Ai Yamamoto",
note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2020",
month = mar,
day = "4",
doi = "10.1016/j.neuron.2019.12.003",
language = "English",
volume = "105",
pages = "813--821.e6",
journal = "Neuron",
issn = "0896-6273",
number = "5",
}