Human Papillomavirus and Epstein-Barr Virus in Head and Neck Lesions

J. S. Lewis, R. D. Chernock

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Viruses are an important factor in many human cancers. In the head and neck region, in particular, human papillomavirus (HPV) and Epstein-Barr virus are critical to understanding the development and cLinical behavior of oropharyngeal and nasopharyngeal carcinomas, respectively. HPV appears to also have a role in the development of many other benign and maLignant neoplasms. As our understanding of the biology of these viruses and of the tumors they cause increases, there is great potential for customized treatments, patient cures, and, most importantly, prevention of these neoplasms.

Original languageEnglish
Title of host publicationPathobiology of Human Disease
Subtitle of host publicationA Dynamic Encyclopedia of Disease Mechanisms
PublisherElsevier Inc.
Number of pages23
ISBN (Electronic)9780123864567
ISBN (Print)9780123864574
StatePublished - Jan 1 2014


  • Adenosquamous
  • Basaloid
  • Epstein-Barr virus
  • Human papillomavirus
  • Immunohistochemistry
  • In situ hybridization
  • Nasopharyngeal carcinoma
  • Nonkeratinizing
  • Oropharyngeal squamous cell carcinoma
  • P16
  • Papillary
  • Reverse transcriptase PCR
  • Schneiderian papilloma
  • Squamous cell carcinoma
  • Squamous papilloma
  • Undifferentiated
  • Verrucous


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