@article{8b949b352f3a42cea8d99897799f4907,
title = "Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site",
abstract = "Powell et al. describe human antibodies that bind to and neutralize multiple distantly related alphaviruses. These antibodies prevent attachment to the Mxra8 alphavirus receptor. Three cryoelectron microscopy structures of Fab in complex with Ross River (RRV), Mayaro, or chikungunya viruses reveal a conserved footprint of the broadly neutralizing mAb RRV-12.",
keywords = "Chikungunya virus, Mayaro virus, O'nyong{\textquoteright}nyong virus, Ross River virus, alphavirus, antibodies, arthritis, cross-reactivity, infectious, viral",
author = "Powell, {Laura A.} and Andrew Miller and Fox, {Julie M.} and Nurgun Kose and Thomas Klose and Kim, {Arthur S.} and Robin Bombardi and Tennekoon, {Rashika N.} and {Dharshan de Silva}, A. and Carnahan, {Robert H.} and Diamond, {Michael S.} and Rossmann, {Michael G.} and Kuhn, {Richard J.} and Crowe, {James E.}",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = nov,
day = "11",
doi = "10.1016/j.chom.2020.07.008",
language = "English",
volume = "28",
pages = "699--711.e7",
journal = "Cell Host and Microbe",
issn = "1931-3128",
number = "5",
}