There is increasing evidence that myeloid cells express several receptor families, which include both inhibitory and stimulatory isoforms. The expression of receptor isoforms with similar specificities but opposite functions on the same cell is intriguing. What might be the interplay between these receptors? Some clues to the answer to this question may come from recent studies on two myeloid receptor families: the ILT/LIR/MIR (immunoglobulin-like transcript/leukocyte Ig-like receptor/monocyte/macrophage Ig-like receptor) and the SIRP (signal- regulatory protein). (C) 2000 Editions scientifiques et medicales Elsevier SAS.

Original languageEnglish
Pages (from-to)323-329
Number of pages7
JournalMicrobes and Infection
Issue number3
StatePublished - Mar 2000


  • Cell surface molecule
  • Dendritic cells
  • Immunoglobulin superfamily
  • MHC
  • Macrophages
  • Monocytes


Dive into the research topics of 'Human inhibitory and activating Ig-like receptors which modulate the function of myeloid cells'. Together they form a unique fingerprint.

Cite this