Human herpesvirus-6 encephalitis following chemotherapy induction for acute myelogenous leukemia

John W. Frey, Joseph N. Cherabie, Maha A. Assi

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We report a case of human herpesvirus-6 (HHV-6) encephalitis in a neutropenic patient who had undergone chemotherapy induction for acute myelogenous leukemia while on broad-spectrum antimicrobial therapy. The patient displayed symptoms of confusion, amnesia, and lethargy. Diagnosis was made via polymerase chain reaction analysis of cerebrospinal fluid. Electroencephalogram and magnetic resonance imaging of the brain were unremarkable. Following diagnosis, the patient was successfully treated with ganciclovir. HHV-6 encephalitis should be considered in immunocompromised patients who become encephalopathic.

Original languageEnglish
Article numbere12756
JournalTransplant Infectious Disease
Volume19
Issue number6
DOIs
StatePublished - Dec 2017

Keywords

  • acute myelogenous leukemia
  • encephalitis
  • human herpesvirus-6
  • immunocompromised

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