@article{db64a97c3c3c48248fb7552a40d61f48,
title = "Human cells and networks of pain: Transforming pain target identification and therapeutic development",
abstract = "Chronic pain is a disabling disease with limited treatment options. While animal models have revealed important aspects of pain neurobiology, therapeutic translation of this knowledge requires our understanding of these cells and networks of pain in humans. We propose a multi-institutional collaboration to rigorously and ethically address this challenge.",
author = "William Renthal and Alexander Chamessian and Michele Curatolo and Steve Davidson and Michael Burton and Sulayman Dib-Hajj and Dougherty, {Patrick M.} and Ebert, {Allison D.} and Gereau, {Robert W.} and Andre Ghetti and Gold, {Michael S.} and Gwendolyn Hoben and Menichella, {Daniela Maria} and Philippe Mercier and Ray, {Wilson Z.} and Daniela Salvemini and Seal, {Rebecca P.} and Stephen Waxman and Woolf, {Clifford J.} and Stucky, {Cheryl L.} and Price, {Theodore J.}",
note = "Funding Information: A.G. is an employee and shareholder of AnaBios. C.J.W. is a founder of Nocion Therapeutics and QurAlis and SAB member at Cygnal Therapeutics and EnClear Therapeutics. M.S.G. has grant support from Grunenthal. S.D. is a founder of Metabodose. T.J.P. is founder of Doloromics and 4E Therapeutics, a shareholder of Acadia Pharma, and a consultant for Biogen and Grunenthal and holds research grants from Merck, Grunenthal, and Hoba Therapeutics. W.R. is a consultant for Kallyope. W.Z.R. receives royalties from Johnson & Johnson, Acera, and Corelink and is a consultant for Globus Medical, Nuvasive, and Syntax. Funding Information: We would like to acknowledge the generous support of the following foundations and agencies: Burroughs Wellcome Fund (W.R.); Migraine Research Foundation (W.R.); Advancing a Healthier Wisconsin (C.L.S.); DoD W81XWH-19-CPMRP-IIRA (M.S.G.); NINDS K08NS101064 (W.R.), R01NS107364 (R.P.S.), R21NS109792 (R.P.S.), RF1NS113881 (S.D.), K22NS096030 (M.D.B.), R01NS104295 (D.M.M.), R35NS105076 (C.J.W.), R01NS070711 (C.L.S.), R37NS108278 (C.L.S.), and R01NS065926 (T.J.P.); NIMH R01AT011447 (C.J.W.); NIGMS R01AR063772 (M.S.G.); NIDDK R01DK107966 (M.S.G.); NCATS UG3TR003090 (M.S.G.); and NIAMS R01AR077691 (D.M.M.). Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",
year = "2021",
month = may,
day = "5",
doi = "10.1016/j.neuron.2021.04.005",
language = "English",
volume = "109",
pages = "1426--1429",
journal = "Neuron",
issn = "0896-6273",
number = "9",
}