TY - GEN
T1 - Human cardiac physiology in the phase plane
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
AU - Eucker, Stephanie
AU - Lisauskas, Jennifer B.
AU - Singh, Jasvindar
AU - Kovacs, Sandor J.
PY - 1999
Y1 - 1999
N2 - Current physiologic parameters acquired during cardiac catheterization include the systolic, minimum, and end-diastolic left ventricular pressures, the ejection fraction, and the maximum and minimum rates of pressure rise and fall. To extract additional physiologic information from the left ventricular pressure (LVP) contour, we utilized phase plane analysis (dP/dt vs P) to study LVP. One cardiac cycle generates a closed loop, or limit-cycle, in the phase plane. We hypothesized that the area of the limit-cycle is related to the external work of the heart, which is a function of both pressure and volume. We investigated the relationship between limit-cycle area (ALC) and ejection fraction (LVEF). LVP and LVEF data acquired during cardiac catheterization in ten subjects were analyzed. We observed a linear relation between ALC and LVEF with an R-value of 0.43. We conclude that new information characterizing LV function can be obtained from ALC.
AB - Current physiologic parameters acquired during cardiac catheterization include the systolic, minimum, and end-diastolic left ventricular pressures, the ejection fraction, and the maximum and minimum rates of pressure rise and fall. To extract additional physiologic information from the left ventricular pressure (LVP) contour, we utilized phase plane analysis (dP/dt vs P) to study LVP. One cardiac cycle generates a closed loop, or limit-cycle, in the phase plane. We hypothesized that the area of the limit-cycle is related to the external work of the heart, which is a function of both pressure and volume. We investigated the relationship between limit-cycle area (ALC) and ejection fraction (LVEF). LVP and LVEF data acquired during cardiac catheterization in ten subjects were analyzed. We observed a linear relation between ALC and LVEF with an R-value of 0.43. We conclude that new information characterizing LV function can be obtained from ALC.
UR - http://www.scopus.com/inward/record.url?scp=0033356959&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0033356959
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 229
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PB - IEEE
Y2 - 13 October 1999 through 16 October 1999
ER -