Human Adaptive Natural Killer Cells: Beyond NKG2C

Julia A. Wagner; Todd A. Fehniger

doi:10.1016/j.it.2016.05.001

Human Adaptive Natural Killer Cells: Beyond NKG2C

Julia A. Wagner
, Todd A. Fehniger

Research output: Contribution to journal › Short survey › peer-review

20 Scopus citations

Abstract

Paradigm-shifting studies have identified NKG2C⁺ adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C^-/- HCMV⁺ individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.

Original language	English
Pages (from-to)	351-353
Number of pages	3
Journal	Trends in Immunology
Volume	37
Issue number	6
DOIs	https://doi.org/10.1016/j.it.2016.05.001
State	Published - Jun 1 2016

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title = "Human Adaptive Natural Killer Cells: Beyond NKG2C",

abstract = "Paradigm-shifting studies have identified NKG2C+ adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C-/- HCMV+ individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.",

author = "Wagner, \{Julia A.\} and Fehniger, \{Todd A.\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Ltd.",

year = "2016",

month = jun,

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doi = "10.1016/j.it.2016.05.001",

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journal = "Trends in Immunology",

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T1 - Human Adaptive Natural Killer Cells

T2 - Beyond NKG2C

AU - Wagner, Julia A.

AU - Fehniger, Todd A.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Paradigm-shifting studies have identified NKG2C+ adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C-/- HCMV+ individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.

AB - Paradigm-shifting studies have identified NKG2C+ adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C-/- HCMV+ individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.

UR - https://www.scopus.com/pages/publications/84969799105

U2 - 10.1016/j.it.2016.05.001

DO - 10.1016/j.it.2016.05.001

M3 - Short survey

C2 - 27179621

AN - SCOPUS:84969799105

SN - 1471-4906

VL - 37

SP - 351

EP - 353

JO - Trends in Immunology

JF - Trends in Immunology

IS - 6

ER -

Human Adaptive Natural Killer Cells: Beyond NKG2C

Abstract

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