Paradigm-shifting studies have identified NKG2C+ adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C-/- HCMV+ individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.

Original languageEnglish
Pages (from-to)351-353
Number of pages3
JournalTrends in Immunology
Issue number6
StatePublished - Jun 1 2016


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