Paradigm-shifting studies have identified NKG2C+ adaptive natural killer (NK) cells in individuals infected with cytomegalovirus. Recently in Cell Reports, Liu et al. demonstrate that NKG2C-/- HCMV+ individuals also generate adaptive NK cells, and reveal CD2 as a major co-stimulatory receptor for these NK cells specialized to respond via FcγRIIIa/CD16.
|Number of pages||3|
|Journal||Trends in Immunology|
|State||Published - Jun 1 2016|