HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells

Keyphrases

• HSPA9 100%
• Tumor Protein p53 (TP53) 100%
• CD34+ Stem Cells 100%
• Mortalin 100%
• Erythroid Maturation 100%
• Myelodysplastic Syndrome 33%
• Knockdown 25%
• CD34+ Cells 25%
• Apoptosis 16%
• Anemia 16%
• Hematopoietic Cells 8%
• Molecular Mechanism 8%
• Gene Knockout 8%
• Bone Marrow Cells 8%
• Gene mutation 8%
• P53 Expression 8%
• Hematopoietic Stem Cells 8%
• Mitochondria 8%
• Heterozygous Deletion 8%
• Large Set 8%
• Heat Shock Proteins 8%
• Pharmacological Inhibitors 8%
• Blood Cancer 8%
• Maturation Defects 8%
• Heterogeneous Groups 8%
• American Adults 8%
• Haploinsufficiency 8%
• Clinical Symptoms 8%
• Cell Maturation 8%
• Chromosome 5 8%
• Long Arm 8%
• Cell Malignancy 8%
• Defect-induced 8%

Biochemistry, Genetics and Molecular Biology

• Maturation 100%
• CD34 100%
• Hematopoietic Cell 100%
• Programmed Cell Death 40%
• Gene Mutation 20%
• P53 20%
• Myeloid 20%
• Heat Shock Protein 20%
• Mitochondrion 20%
• Haploinsufficiency 20%
• Cell Maturation 20%
• Chromosome 5 20%
• Gene Knockdown 20%