A critical component of the stress fracture healing response is a proportional increase in periosteal vascularity before bone deposition. The molecular factors that coordinate the angiogenic-osteogenic response to a stress fracture have been recently described. Bone morphogenetic protein-2 may be an important early response gene in the initiation of periosteal woven bone formation.

Original languageEnglish
Number of pages1
JournalJournal of the American Academy of Orthopaedic Surgeons
Issue number1
StatePublished - Jan 1 2009


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