TY - JOUR
T1 - How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)?
AU - Mein, S.
AU - Rankine, L.
AU - Miles, D.
AU - Juang, T.
AU - Cai, B.
AU - Curcuru, A.
AU - Mutic, S.
AU - Fenoli, J.
AU - Adamovics, J.
AU - Li, H.
AU - Oldham, M.
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2017/6/5
Y1 - 2017/6/5
N2 - To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MR-compatibility, and energy-independence. An open calibration field and symmetrical 3-field plans were delivered to 10cm diameter PRESAGE® to examine percent depth dose and response uniformity under a magnetic field. Evidence of non-linear dose response led to a large volume PRESAGE® study where small corrections were developed for temporally- and spatially-dependent behaviors observed between irradiation and delayed readout. TG-119 plans were created in the MRIdian® TPS and then delivered to 14.5cm 2kg PRESAGE® dosimeters. Through the domestic investigation of an off-site MRgRT system, a refined 3D remote dosimetry protocol is presented capable of validation of advanced MRgRT radiation treatments.
AB - To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MR-compatibility, and energy-independence. An open calibration field and symmetrical 3-field plans were delivered to 10cm diameter PRESAGE® to examine percent depth dose and response uniformity under a magnetic field. Evidence of non-linear dose response led to a large volume PRESAGE® study where small corrections were developed for temporally- and spatially-dependent behaviors observed between irradiation and delayed readout. TG-119 plans were created in the MRIdian® TPS and then delivered to 14.5cm 2kg PRESAGE® dosimeters. Through the domestic investigation of an off-site MRgRT system, a refined 3D remote dosimetry protocol is presented capable of validation of advanced MRgRT radiation treatments.
UR - https://www.scopus.com/pages/publications/85021906457
U2 - 10.1088/1742-6596/847/1/012056
DO - 10.1088/1742-6596/847/1/012056
M3 - Conference article
AN - SCOPUS:85021906457
SN - 1742-6588
VL - 847
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012056
T2 - 9th International Conference on 3D Radiation Dosimetry, IC3DDose 2016
Y2 - 7 November 2016 through 10 November 2016
ER -