How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)?

S. Mein, L. Rankine, D. Miles, T. Juang, B. Cai, A. Curcuru, S. Mutic, J. Fenoli, J. Adamovics, H. Li, M. Oldham

Research output: Contribution to journalConference article

1 Scopus citations

Abstract

To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MR-compatibility, and energy-independence. An open calibration field and symmetrical 3-field plans were delivered to 10cm diameter PRESAGE® to examine percent depth dose and response uniformity under a magnetic field. Evidence of non-linear dose response led to a large volume PRESAGE® study where small corrections were developed for temporally- and spatially-dependent behaviors observed between irradiation and delayed readout. TG-119 plans were created in the MRIdian® TPS and then delivered to 14.5cm 2kg PRESAGE® dosimeters. Through the domestic investigation of an off-site MRgRT system, a refined 3D remote dosimetry protocol is presented capable of validation of advanced MRgRT radiation treatments.

Original languageEnglish
Article number012056
JournalJournal of Physics: Conference Series
Volume847
Issue number1
DOIs
StatePublished - Jun 5 2017
Event9th International Conference on 3D Radiation Dosimetry, IC3DDose 2016 - Galveston, United States
Duration: Nov 7 2016Nov 10 2016

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    Mein, S., Rankine, L., Miles, D., Juang, T., Cai, B., Curcuru, A., Mutic, S., Fenoli, J., Adamovics, J., Li, H., & Oldham, M. (2017). How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)? Journal of Physics: Conference Series, 847(1), [012056]. https://doi.org/10.1088/1742-6596/847/1/012056