Abstract
Urinary tract infections pose a serious health threat with respect to antibiotic resistance and high recurrence rates. While the host robustly responds to bacterial infiltration into the bladder, uropathogenic Escherichia coli can survive the onslaught to persist for months after initially infecting. To accomplish this feat, uropathogenic E. coli forms intracellular bacterial communities, with many biofilm-like properties, within the bladder epithelium. These communities may allow bacteria to subvert host defenses and form a persistent reservoir in the bladder.
| Original language | English |
|---|---|
| Pages (from-to) | 1094-1101 |
| Number of pages | 8 |
| Journal | Microbes and Infection |
| Volume | 6 |
| Issue number | 12 |
| DOIs | |
| State | Published - Oct 2004 |
Keywords
- Biofilm
- Bladder
- Intracellular
- Recurrent
- Urinary tract infection
- Uropathogenic Escherichia coli
Fingerprint Dive into the research topics of 'Host subversion by formation of intracellular bacterial communities in the urinary tract'. Together they form a unique fingerprint.
Cite this
Anderson, G. G., Martin, S. M., & Hultgren, S. J. (2004). Host subversion by formation of intracellular bacterial communities in the urinary tract. Microbes and Infection, 6(12), 1094-1101. https://doi.org/10.1016/j.micinf.2004.05.023