Host autophagy combating S. aureus: α-toxin will be tolerated

Michael E. Powers, Juliane Bubeck Wardenburg

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations

Abstract

Autophagy regulates the degradation of both cellular components and invading intracellular pathogens. In this issue of Cell Host & Microbe, Maurer et al. (2015) reveal that cellular autophagy decreases host sensitivity to Staphylococcus aureus α-toxin via reduced expression of the toxin receptor ADAM10, thus rendering the host tolerant to disease.

Original languageEnglish
Pages (from-to)419-420
Number of pages2
JournalCell Host and Microbe
Volume17
Issue number4
DOIs
StatePublished - Apr 8 2015

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