Homing in on a biological joint replacement

Farshid Guilak

doi:10.1186/scrt40

Homing in on a biological joint replacement

Farshid Guilak

Research output: Contribution to journal › Review article

6 Scopus citations

Abstract

The use of tissue engineering therapies for treating damaged articular cartilage has traditionally focused on cell-based therapies for the repair of focal chondral or osteochondral defects. A recent study by Lee and colleagues in the Lancet shows exciting proof-of-concept that an acellular scaffold containing transforming growth factor beta 3 can induce homing of cells that regenerate a hyaline-like cartilage surface. These findings provide a glimpse into the possibility that tissue engineering may in fact provide the means for regeneration of an entire joint surface, beyond a simple focal defect in the articular cartilage.

Original language	English
Article number	40
Journal	Stem Cell Research and Therapy
Volume	1
Issue number	5
DOIs	https://doi.org/10.1186/scrt40
State	Published - Dec 1 2010
Externally published	Yes

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10.1186/scrt40

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Guilak, F. (2010). Homing in on a biological joint replacement. Stem Cell Research and Therapy, 1(5), [40]. https://doi.org/10.1186/scrt40

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