TY - JOUR
T1 - Home and school pollutant exposure, respiratory outcomes, and influence of historical redlining
AU - Jung, Kyung Hwa
AU - Argenio, Kira L.
AU - Jackson, Daniel J.
AU - Miller, Rachel L.
AU - Perzanowski, Matthew S.
AU - Rundle, Andrew G.
AU - Bacharier, Leonard B.
AU - Busse, William W.
AU - Cohen, Robyn T.
AU - Visness, Cynthia M.
AU - Gill, Michelle A.
AU - Gruchalla, Rebecca S.
AU - Hershey, Gurjit K.
AU - Kado, Rachel K.
AU - Sherenian, Michael G.
AU - Liu, Andrew H.
AU - Makhija, Melanie M.
AU - Pillai, Dinesh K.
AU - Rivera-Spoljaric, Katherine
AU - Gergen, Peter J.
AU - Altman, Matthew C.
AU - Sandel, Megan T.
AU - Sorkness, Christine A.
AU - Kattan, Meyer
AU - Lovinsky-Desir, Stephanie
N1 - Publisher Copyright:
© 2024 American Academy of Allergy, Asthma & Immunology
PY - 2024/11
Y1 - 2024/11
N2 - Background: The discriminatory and racist policy of historical redlining in the United States during the 1930s played a role in perpetuating contemporary environmental health disparities. Objective: Our objectives were to determine associations between home and school pollutant exposure (fine particulate matter [PM2.5], NO2) and respiratory outcomes (Composite Asthma Severity Index, lung function) among school-aged children with asthma and examine whether associations differed between children who resided and/or attended school in historically redlined compared to non-redlined neighborhoods. Methods: Children ages 6 to 17 with moderate-to-severe asthma (N = 240) from 9 US cities were included. Combined home and school exposure to PM2.5 and NO2 was calculated based on geospatially assessed monthly averaged outdoor pollutant concentrations. Repeated measures of Composite Asthma Severity Index and lung function were collected. Results: Overall, 37.5% of children resided and/or attended schools in historically redlined neighborhoods. Children in historically redlined neighborhoods had greater exposure to NO2 (median: 15.4 vs 12.1 parts per billion) and closer distance to a highway (median: 0.86 vs 1.23 km), compared to those in non-redlined neighborhoods (P < .01). Overall, PM2.5 was not associated with asthma severity or lung function. However, among children in redlined neighborhoods, higher PM2.5 was associated with worse asthma severity (P < .005). No association was observed between pollutants and lung function or asthma severity among children in non-redlined neighborhoods (P > .005). Conclusions: Our findings highlight the significance of historical redlining and current environmental health disparities among school-aged children with asthma, specifically, the environmental injustice of PM2.5 exposure and its associations with respiratory health.
AB - Background: The discriminatory and racist policy of historical redlining in the United States during the 1930s played a role in perpetuating contemporary environmental health disparities. Objective: Our objectives were to determine associations between home and school pollutant exposure (fine particulate matter [PM2.5], NO2) and respiratory outcomes (Composite Asthma Severity Index, lung function) among school-aged children with asthma and examine whether associations differed between children who resided and/or attended school in historically redlined compared to non-redlined neighborhoods. Methods: Children ages 6 to 17 with moderate-to-severe asthma (N = 240) from 9 US cities were included. Combined home and school exposure to PM2.5 and NO2 was calculated based on geospatially assessed monthly averaged outdoor pollutant concentrations. Repeated measures of Composite Asthma Severity Index and lung function were collected. Results: Overall, 37.5% of children resided and/or attended schools in historically redlined neighborhoods. Children in historically redlined neighborhoods had greater exposure to NO2 (median: 15.4 vs 12.1 parts per billion) and closer distance to a highway (median: 0.86 vs 1.23 km), compared to those in non-redlined neighborhoods (P < .01). Overall, PM2.5 was not associated with asthma severity or lung function. However, among children in redlined neighborhoods, higher PM2.5 was associated with worse asthma severity (P < .005). No association was observed between pollutants and lung function or asthma severity among children in non-redlined neighborhoods (P > .005). Conclusions: Our findings highlight the significance of historical redlining and current environmental health disparities among school-aged children with asthma, specifically, the environmental injustice of PM2.5 exposure and its associations with respiratory health.
KW - Home environment
KW - asthma disparities
KW - asthma severity
KW - combined home and school exposure
KW - composite asthma severity index
KW - lung function
KW - school environment
KW - traffic-related air pollution
UR - http://www.scopus.com/inward/record.url?scp=85200998523&partnerID=8YFLogxK
U2 - 10.1016/j.jaci.2024.06.020
DO - 10.1016/j.jaci.2024.06.020
M3 - Article
C2 - 38992473
AN - SCOPUS:85200998523
SN - 0091-6749
VL - 154
SP - 1159
EP - 1168
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
IS - 5
ER -