Hold tight (but not too tight) to get it right: Accurate bypass of an 8-oxoguanine lesion by DNA polymerase β

Luis G. Brieba; Tom Ellenberger

doi:10.1016/S0969-2126(02)00917-6

Hold tight (but not too tight) to get it right: Accurate bypass of an 8-oxoguanine lesion by DNA polymerase β

Luis G. Brieba, Tom Ellenberger

Department of Biochemistry & Molecular Biophysics

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Crystal structures of DNA polymerase β encountering an 8-oxoguanine lesion show how the polymerase selects an otherwise unfavorable conformation of a damaged template base to enable error-free bypass.

Original language	English
Pages (from-to)	1-2
Number of pages	2
Journal	Structure
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/S0969-2126(02)00917-6
State	Published - Jan 1 2003

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title = "Hold tight (but not too tight) to get it right: Accurate bypass of an 8-oxoguanine lesion by DNA polymerase β",

abstract = "Crystal structures of DNA polymerase β encountering an 8-oxoguanine lesion show how the polymerase selects an otherwise unfavorable conformation of a damaged template base to enable error-free bypass.",

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AB - Crystal structures of DNA polymerase β encountering an 8-oxoguanine lesion show how the polymerase selects an otherwise unfavorable conformation of a damaged template base to enable error-free bypass.

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Hold tight (but not too tight) to get it right: Accurate bypass of an 8-oxoguanine lesion by DNA polymerase β

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