hnRNP C1/C2 and pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang

Keyphrases

• Oligonucleotides 100%
• HnRNP 100%
• C1-C2 100%
• Senescence 100%
• Beta-proteins 100%
• T-oligo 100%
• Telomere Overhang 100%
• DNA Damage Response 33%
• Binding Protein 25%
• Purine 25%
• Knockdown 16%
• Mass Spectrometry 16%
• Non-small Cell Lung Cancer (NSCLC) 16%
• Cancer Therapeutics 16%
• Melanoma Cells 16%
• E2F Transcription Factor 1 (E2F1) 16%
• Complementary Oligonucleotide 16%
• Phosphorylation 8%
• Non-small Cell Lung Cancer Cells 8%
• Senescence-associated 8%
• DNA Binding 8%
• Immunoblotting 8%
• RNA Binding 8%
• Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) 8%
• Cell Lysate 8%
• Overhang 8%
• Telomere 8%
• Melanoma 8%
• Protein Bands 8%
• Anticancer Effect 8%
• NBS1 8%
• Induced Senescence 8%
• Telomere Biology 8%
• Ataxia Telangiectasia mutated 8%
• Ribonucleic Acid 8%
• Senescence Cells 8%
• β-galactosidase Assay 8%
• Short Hairpin 8%
• Oligo-MM 8%
• H358 8%

Biochemistry, Genetics and Molecular Biology

• Oligonucleotide 100%
• DNA Damage Response 100%
• Telomere 100%
• P53 75%
• Binding Protein 75%
• Mass Spectrometry 50%
• E2F1 50%
• Upregulation 25%
• Cancer Cell 25%
• DNA Binding 25%
• Anticancer 25%
• RNA Binding 25%
• Cell Lysate 25%
• Polyacrylamide Gel Electrophoresis 25%
• P21 25%
• Small Hairpin RNA 25%
• Ribonucleoprotein 25%
• Ataxia Telangiectasia Mutated 25%
• P73 25%
• Senescence-Associated Beta-Galactosidase 25%
• Immunoblotting 25%