History of prostate-specific antigen, from detection to overdiagnosis

Brandon J. Manley; Gerald L. Andriole

doi:10.1007/978-3-319-21485-6_1

History of prostate-specific antigen, from detection to overdiagnosis

Brandon J. Manley, Gerald L. Andriole

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

The history of prostate-specific antigen (PSA) is full of significant discoveries that have revolutionized the diagnosis and management of prostate cancer. In this chapter we summarize the history of the discovery of PSA and how it became such an integral part of prostate cancer management. Basic biology and physiology of PSA will also be discussed to provide insight about its current and future applications. The use of PSA to screen for prostate cancer remains a controversial topic of debate and in this chapter we present some of the salient points in the arguments for and against the use of PSA screening. This chapter provides a focused literature review of the benefits and risks of PSA screening and a basis for its current recommendations for prostate cancer early detection.

Original language	English
Title of host publication	The Prostate Cancer Dilemma
Subtitle of host publication	Selecting Patients for Active Surveillance, Focal Ablation and Definitive Therapy
Publisher	Springer International Publishing
Pages	3-16
Number of pages	14
ISBN (Electronic)	9783319214856
ISBN (Print)	9783319214849
DOIs	https://doi.org/10.1007/978-3-319-21485-6_1
State	Published - Jan 1 2016

Access to Document

10.1007/978-3-319-21485-6_1

Cite this

@inbook{f1c32d1460de49d7a9055785b7c11f5f,

title = "History of prostate-specific antigen, from detection to overdiagnosis",

abstract = "The history of prostate-specific antigen (PSA) is full of significant discoveries that have revolutionized the diagnosis and management of prostate cancer. In this chapter we summarize the history of the discovery of PSA and how it became such an integral part of prostate cancer management. Basic biology and physiology of PSA will also be discussed to provide insight about its current and future applications. The use of PSA to screen for prostate cancer remains a controversial topic of debate and in this chapter we present some of the salient points in the arguments for and against the use of PSA screening. This chapter provides a focused literature review of the benefits and risks of PSA screening and a basis for its current recommendations for prostate cancer early detection.",

author = "Manley, {Brandon J.} and Andriole, {Gerald L.}",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2016.",

year = "2016",

month = jan,

day = "1",

doi = "10.1007/978-3-319-21485-6_1",

language = "English",

isbn = "9783319214849",

pages = "3--16",

booktitle = "The Prostate Cancer Dilemma",

publisher = "Springer International Publishing",

}

TY - CHAP

T1 - History of prostate-specific antigen, from detection to overdiagnosis

AU - Manley, Brandon J.

AU - Andriole, Gerald L.

N1 - Publisher Copyright: © Springer International Publishing Switzerland 2016.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - The history of prostate-specific antigen (PSA) is full of significant discoveries that have revolutionized the diagnosis and management of prostate cancer. In this chapter we summarize the history of the discovery of PSA and how it became such an integral part of prostate cancer management. Basic biology and physiology of PSA will also be discussed to provide insight about its current and future applications. The use of PSA to screen for prostate cancer remains a controversial topic of debate and in this chapter we present some of the salient points in the arguments for and against the use of PSA screening. This chapter provides a focused literature review of the benefits and risks of PSA screening and a basis for its current recommendations for prostate cancer early detection.

AB - The history of prostate-specific antigen (PSA) is full of significant discoveries that have revolutionized the diagnosis and management of prostate cancer. In this chapter we summarize the history of the discovery of PSA and how it became such an integral part of prostate cancer management. Basic biology and physiology of PSA will also be discussed to provide insight about its current and future applications. The use of PSA to screen for prostate cancer remains a controversial topic of debate and in this chapter we present some of the salient points in the arguments for and against the use of PSA screening. This chapter provides a focused literature review of the benefits and risks of PSA screening and a basis for its current recommendations for prostate cancer early detection.

UR - http://www.scopus.com/inward/record.url?scp=84956789124&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-21485-6_1

DO - 10.1007/978-3-319-21485-6_1

M3 - Chapter

AN - SCOPUS:84956789124

SN - 9783319214849

SP - 3

EP - 16

BT - The Prostate Cancer Dilemma

PB - Springer International Publishing

ER -

History of prostate-specific antigen, from detection to overdiagnosis

Abstract

Access to Document

Other files and links

Fingerprint

Cite this