Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness

Keyphrases

• Clear Cell Renal Cell Carcinoma (ccRCC) 100%
• Proteogenomics 100%
• Aggressiveness 100%
• Intratumoral Heterogeneity 60%
• Tumor 20%
• Effective Treatment 20%
• Proteomic Analysis 20%
• Phosphoproteomics 20%
• Specificity Protein 1 20%
• Tumor Grade 20%
• Histologic 20%
• UCHL1 20%
• Prognostic Value 20%
• High-risk Disease 20%
• Histological Analysis 20%
• Treatment Outcome 20%
• Histological Subtypes 20%
• Treatment Strategy 20%
• Hypermethylation 20%
• Immune Signature 20%
• Comprehensive Profile 20%
• Gene Signature 20%
• Genome Analysis 20%
• Prognosis Outcome 20%
• Tumor Evolution 20%
• Molecular Profile 20%
• Genomic Instability 20%
• Single-nucleus RNA Sequencing 20%
• Rhabdoid Features 20%
• BAP1 mutation 20%
• Non-tumor Tissue 20%
• Sarcomatoid 20%
• Protein Glycosylation 20%
• Disease Subsets 20%
• In Vitro Cell Line 20%
• Cell Line Study 20%

Medicine and Dentistry

• Neoplasm 100%
• Clear Cell Renal Cell Carcinoma 100%
• Proteogenomics 100%
• RNA Sequence 33%
• In Vitro 33%
• Disease 33%
• Protein 33%
• Genomic Instability 33%
• Metabolomics 33%
• Nuclear RNA 33%
• Sarcomatoid 33%
• Protein Glycosylation 33%
• Cell Line Study 33%

Biochemistry, Genetics and Molecular Biology

• Proteogenomics 100%
• BAP1 50%
• RNA Sequence 50%
• Genome Instability 50%
• Metabolomics 50%
• Gene Signature 50%
• Protein Glycosylation 50%