Histocompatibility studies in psoriasis vulgaris: Family studies

L. R. Espinoza, C. Bombardier, S. W. Gaylord, S. Lauter, F. B. Vasey, C. K. Osterland

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11 Scopus citations

Abstract

A significant correlation between certain histocompatibility antigens, psoriasis and psoriatic arthritis is well established. Familial studies of psoriatic patients have shown a familial aggregation of psoriasis and psoriatic arthritis. In the present investigation, we studied 2 families in which psoriasis and/or psoriatic arthritis were seen in several members of different generations. HLA typing and mixed lymphocyte culture studies were performed. The results provide further documentation of the complexity of the genetic influences in psoriatic arthritis and psoriasis.

Original languageEnglish
Pages (from-to)445-452
Number of pages8
JournalJournal of Rheumatology
Volume7
Issue number4
StatePublished - Dec 1 1980
Externally publishedYes

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    Espinoza, L. R., Bombardier, C., Gaylord, S. W., Lauter, S., Vasey, F. B., & Osterland, C. K. (1980). Histocompatibility studies in psoriasis vulgaris: Family studies. Journal of Rheumatology, 7(4), 445-452.