TY - JOUR
T1 - Histiocytic Necrotizing Lymphadenitis (Kikuchi's Disease)
AU - Piccirillo, Jay F.
AU - Lanza, Donald C.
AU - Stasio, Edward A.
AU - Moloy, Peter J.
PY - 1991/7
Y1 - 1991/7
N2 - • Histiocytic necrotizing lymphandenitis (HNL), or Kikuchi's disease, is a newly recognized disease of unknown origin that causes cervical lymphadenitis, usually in young women. Initially described in Japan, cases of HNL are being reported in the United States and other western countries with increasing frequency. Symptoms of HNL include tender cervical adenopathy, fever, weight loss, and night sweats. Laboratory studies reveal leukopenia with relative granulocytopenia and lymphocytosis. Lymph node biopsy reveals areas with frank cellular necrosis, karyorrhexis, and absence of plasma cells. The histologic features of HNL are distinctive but can be confused with those of lymphoma. We describe two cases of HNL and present recommendations for diagnosis and treatment. (Arch Otolaryngol Head Neck Surg. 1991;117:800-802)
AB - • Histiocytic necrotizing lymphandenitis (HNL), or Kikuchi's disease, is a newly recognized disease of unknown origin that causes cervical lymphadenitis, usually in young women. Initially described in Japan, cases of HNL are being reported in the United States and other western countries with increasing frequency. Symptoms of HNL include tender cervical adenopathy, fever, weight loss, and night sweats. Laboratory studies reveal leukopenia with relative granulocytopenia and lymphocytosis. Lymph node biopsy reveals areas with frank cellular necrosis, karyorrhexis, and absence of plasma cells. The histologic features of HNL are distinctive but can be confused with those of lymphoma. We describe two cases of HNL and present recommendations for diagnosis and treatment. (Arch Otolaryngol Head Neck Surg. 1991;117:800-802)
UR - http://www.scopus.com/inward/record.url?scp=0025851349&partnerID=8YFLogxK
U2 - 10.1001/archotol.1991.01870190112024
DO - 10.1001/archotol.1991.01870190112024
M3 - Article
C2 - 1863449
AN - SCOPUS:0025851349
SN - 0886-4470
VL - 117
SP - 800
EP - 802
JO - Archives of Otolaryngology--Head and Neck Surgery
JF - Archives of Otolaryngology--Head and Neck Surgery
IS - 7
ER -