High-throughput fiber-array transvaginal ultrasound/photoacoustic probe for ovarian cancer imaging

  • Hassan S. Salehi
  • , Patrick D. Kumavor
  • , Umar Alqasemi
  • , Hai Li
  • , Tianheng Wang
  • , Quing Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Scopus citations

Abstract

A high-throughput ultrasound/photoacoustic probe for delivering high contrast and signal-to-noise ratio images was designed, constructed, and tested. The probe consists of a transvaginal ultrasound array integrated with four 1mm-core optical fibers and a sheath. The sheath encases transducer and is lined with highly reflecting aluminum for high intensity light output and uniformity while at the same time remaining below the maximum permissible exposure (MPE) recommended by the American National Standards Institute (ANSI). The probe design was optimized by simulating the light fluence distribution in Zemax. The performance of the probe was evaluated by experimental measurements of the fluence and real-time imaging of polyethylene-tubing filled with blood. These results suggest that our probe has great potential for in vivo imaging and characterization of ovarian cancer.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2014
PublisherSPIE
ISBN (Print)9780819498564
DOIs
StatePublished - 2014
EventPhotons Plus Ultrasound: Imaging and Sensing 2014 - San Francisco, CA, United States
Duration: Feb 2 2014Feb 5 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8943
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2014
Country/TerritoryUnited States
CitySan Francisco, CA
Period02/2/1402/5/14

Keywords

  • Fiber array
  • High efficient light delivery
  • Light fluence distribution
  • Ovarian cancer
  • Photoacoustic imaging
  • Transvaginal ultrasound probe

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