High-throughput discovery of rare insertions and deletions in large cohorts

Keyphrases

• Large Cohort 100%
• Rare Variants 100%
• Large Pools 100%
• Significance Threshold 100%
• High-throughput Discovery 100%
• Sequence Method 50%
• DNA Sequencing 50%
• High Specificity 50%
• Genetic Disease 50%
• Sequence Data 50%
• High Sensitivity 50%
• Variant Frequency 50%
• Computational Approach 50%
• Cause of Disease 50%
• Experimental Strategies 50%
• Novel Disease 50%
• DNA-encoded Library 50%
• Existing Algorithms 50%
• Information Integration 50%
• Pooled Sequencing 50%
• Computational Strategies 50%
• Pooled DNA 50%
• Value Change 50%
• Cost Effect 50%
• Synthetic Library 50%
• Effect-directed Detection 50%

Biochemistry, Genetics and Molecular Biology

• Indel 100%
• Rare Variant 50%
• Genetic Disorder 25%
• DNA Sequence 25%
• DNA Library 25%
• Genotyping 25%