High-resolution NMR in inhomogeneous fields

John J. Balbach; Mark S. Conradi; D. P. Cistola; Changguo Tang; Joel R. Garbow; W. C. Hutton

doi:10.1016/S0009-2614(97)00858-0

High-resolution NMR in inhomogeneous fields

John J. Balbach, Mark S. Conradi, D. P. Cistola, Changguo Tang, Joel R. Garbow, W. C. Hutton

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

A new NMR technique is presented that yields high-resolution, 1-D NMR spectra of solutes in inhomogeneous magnetic fields. The method exploits the nuclear Overhauser effect which couples the longitudinal relaxation of solvent and solute nuclear spins. Effectively, the solvent spins serve as reporters or local gaussmeters for the solute spins. Both 2-D and 1-D versions of this new experiment are reported. Potential applications of the method include in vivo NMR spectroscopy, where the field homogeneity is always degraded by the magnetic susceptibilities of the various tissues.

Original language	English
Pages (from-to)	367-374
Number of pages	8
Journal	Chemical Physics Letters
Volume	277
Issue number	4
DOIs	https://doi.org/10.1016/S0009-2614(97)00858-0
State	Published - Oct 10 1997

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title = "High-resolution NMR in inhomogeneous fields",

abstract = "A new NMR technique is presented that yields high-resolution, 1-D NMR spectra of solutes in inhomogeneous magnetic fields. The method exploits the nuclear Overhauser effect which couples the longitudinal relaxation of solvent and solute nuclear spins. Effectively, the solvent spins serve as reporters or local gaussmeters for the solute spins. Both 2-D and 1-D versions of this new experiment are reported. Potential applications of the method include in vivo NMR spectroscopy, where the field homogeneity is always degraded by the magnetic susceptibilities of the various tissues.",

author = "Balbach, {John J.} and Conradi, {Mark S.} and Cistola, {D. P.} and Changguo Tang and Garbow, {Joel R.} and Hutton, {W. C.}",

note = "Funding Information: The authors are grateful for helpful conversations with J.J.H. Ackerman, R.E. Norberg, A. Bax, K. Hall and A. Pines. The work was partially supported by NSF grant DMR 94-03667.",

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T1 - High-resolution NMR in inhomogeneous fields

AU - Balbach, John J.

AU - Conradi, Mark S.

AU - Cistola, D. P.

AU - Tang, Changguo

AU - Garbow, Joel R.

AU - Hutton, W. C.

N1 - Funding Information: The authors are grateful for helpful conversations with J.J.H. Ackerman, R.E. Norberg, A. Bax, K. Hall and A. Pines. The work was partially supported by NSF grant DMR 94-03667.

PY - 1997/10/10

Y1 - 1997/10/10

N2 - A new NMR technique is presented that yields high-resolution, 1-D NMR spectra of solutes in inhomogeneous magnetic fields. The method exploits the nuclear Overhauser effect which couples the longitudinal relaxation of solvent and solute nuclear spins. Effectively, the solvent spins serve as reporters or local gaussmeters for the solute spins. Both 2-D and 1-D versions of this new experiment are reported. Potential applications of the method include in vivo NMR spectroscopy, where the field homogeneity is always degraded by the magnetic susceptibilities of the various tissues.

AB - A new NMR technique is presented that yields high-resolution, 1-D NMR spectra of solutes in inhomogeneous magnetic fields. The method exploits the nuclear Overhauser effect which couples the longitudinal relaxation of solvent and solute nuclear spins. Effectively, the solvent spins serve as reporters or local gaussmeters for the solute spins. Both 2-D and 1-D versions of this new experiment are reported. Potential applications of the method include in vivo NMR spectroscopy, where the field homogeneity is always degraded by the magnetic susceptibilities of the various tissues.

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DO - 10.1016/S0009-2614(97)00858-0

M3 - Article

AN - SCOPUS:0031563706

SN - 0009-2614

VL - 277

SP - 367

EP - 374

JO - Chemical Physics Letters

JF - Chemical Physics Letters

IS - 4

ER -

High-resolution NMR in inhomogeneous fields

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