TY - JOUR
T1 - High-density-lipoprotein cholesterol in bodybuilders v powerlifters. Negative effects of androgen use
AU - Hurley, B. F.
AU - Seals, D. R.
AU - Hagberg, J. M.
AU - Goldberg, Anne
AU - Ostrove, S. M.
AU - Holloszy, J. O.
AU - Wiest, W. G.
AU - Goldberg, A. P.
PY - 1984/9/6
Y1 - 1984/9/6
N2 -
To determine the relationship between profiles and the type of weight training and to assess the effects of anabolic-androgenic steroids on lipids, bodybuilders and powerlifters of similar age, body fat, and testosterone levels were studied before and after androgen use. Before androgen administration powerlifters had lower levels of plasma high-density-lipoprotein cholesterol (HDL-C) and HDL
2
-C (38 ± 2; 6 ± 1 mg/dL; (X) ± SE, n=8) than bodybuilders (55 ± 2; 12 ± 1 mg/dL; n=8) and runners of comparable age and body fat (47 ± 2; 14 ± 2 mg/dL; n=8), while levels of low-density-lipoprotein cholesterol (LDL-C) were higher in powerlifters (138 ± 10 mg/dL) than in bodybuilders (104 ± 7 mg/dL) and runners (110 ± 6 mg/dL). Therefore, powerlifters had higher LDL-C/HDL-C ratios (3.7 ± 0.3) than bodybuilders (2.0 ± 0.2) and runners (2.4 ± 0.2). Androgen use by eight bodybuilders and four powerlifters lowered values of both HDL-C and HDL
2
-C by 55% and raised values of LDL-C (61% ± 10%) and LDL-C/HDL-C ratios (280% ± 40%). Therefore, the training regimen of bodybuilders is associated with a more favorable lipid profile than the training used by powerlifters. Androgen use by strength-trained athletes may increase their risk for coronary heart disease.
AB -
To determine the relationship between profiles and the type of weight training and to assess the effects of anabolic-androgenic steroids on lipids, bodybuilders and powerlifters of similar age, body fat, and testosterone levels were studied before and after androgen use. Before androgen administration powerlifters had lower levels of plasma high-density-lipoprotein cholesterol (HDL-C) and HDL
2
-C (38 ± 2; 6 ± 1 mg/dL; (X) ± SE, n=8) than bodybuilders (55 ± 2; 12 ± 1 mg/dL; n=8) and runners of comparable age and body fat (47 ± 2; 14 ± 2 mg/dL; n=8), while levels of low-density-lipoprotein cholesterol (LDL-C) were higher in powerlifters (138 ± 10 mg/dL) than in bodybuilders (104 ± 7 mg/dL) and runners (110 ± 6 mg/dL). Therefore, powerlifters had higher LDL-C/HDL-C ratios (3.7 ± 0.3) than bodybuilders (2.0 ± 0.2) and runners (2.4 ± 0.2). Androgen use by eight bodybuilders and four powerlifters lowered values of both HDL-C and HDL
2
-C by 55% and raised values of LDL-C (61% ± 10%) and LDL-C/HDL-C ratios (280% ± 40%). Therefore, the training regimen of bodybuilders is associated with a more favorable lipid profile than the training used by powerlifters. Androgen use by strength-trained athletes may increase their risk for coronary heart disease.
UR - http://www.scopus.com/inward/record.url?scp=0021179914&partnerID=8YFLogxK
U2 - 10.1001/jama.252.4.507
DO - 10.1001/jama.252.4.507
M3 - Article
C2 - 6737643
VL - 252
SP - 507
EP - 513
JO - Journal of the American Medical Association
JF - Journal of the American Medical Association
SN - 0098-7484
IS - 4
ER -