TY - JOUR
T1 - Heterotrimeric G-Protein Signaling in Plants
T2 - Conserved and Novel Mechanisms
AU - Pandey, Sona
N1 - Funding Information:
The author sincerely thanks several colleagues for multiple rounds of discussion during the writing of this review article and especially Dr. Elizabeth Kellogg (Donald Danforth Plant Science Center) for critical reading of the manuscript. She also apologizes to the colleagues whose work could not be cited due to space constraints. Research in the author’s laboratory is supported by the National Institute of Food and Agriculture through the Agriculture and Food Research Initiative (2015-67013-22964) and by grants from the National Science Foundation Division of Integrative Organismal Systems (1557942) and Division of Molecular and Cellular Bioscience (1714693).
Publisher Copyright:
© 2019 by Annual Reviews. All rights reserved.
PY - 2019/4
Y1 - 2019/4
N2 - Heterotrimeric GTP-binding proteins are key regulators of a multitude of signaling pathways in all eukaryotes. Although the core G-protein components and their basic biochemistries are broadly conserved throughout evolution, the regulatory mechanisms of G proteins seem to have been rewired in plants to meet specific needs. These proteins are currently the focus of intense research in plants due to their involvement in many agronomically important traits, such as seed yield, organ size regulation, biotic and abiotic stress responses, symbiosis, and nitrogen use efficiency. The availability of massive sequence information from a variety of plant species, extensive biochemical data generated over decades, and impressive genetic resources for plant G proteins have made it possible to examine their role, unique properties, and novel regulation. This review focuses on some recent advances in our understanding of the mechanistic details of this critical signaling pathway to enable the precise manipulation and generation of plants to meet future needs.
AB - Heterotrimeric GTP-binding proteins are key regulators of a multitude of signaling pathways in all eukaryotes. Although the core G-protein components and their basic biochemistries are broadly conserved throughout evolution, the regulatory mechanisms of G proteins seem to have been rewired in plants to meet specific needs. These proteins are currently the focus of intense research in plants due to their involvement in many agronomically important traits, such as seed yield, organ size regulation, biotic and abiotic stress responses, symbiosis, and nitrogen use efficiency. The availability of massive sequence information from a variety of plant species, extensive biochemical data generated over decades, and impressive genetic resources for plant G proteins have made it possible to examine their role, unique properties, and novel regulation. This review focuses on some recent advances in our understanding of the mechanistic details of this critical signaling pathway to enable the precise manipulation and generation of plants to meet future needs.
KW - G protein-coupled receptor
KW - GAP
KW - GTPase
KW - GTPase activity-accelerating protein
KW - guanine nucleotide exchange factor
KW - heterotrimeric G protein
KW - phospholipase
KW - receptor-like cytoplasmic kinase
KW - receptor-like kinase
KW - regulator of G-protein signaling
UR - http://www.scopus.com/inward/record.url?scp=85065056884&partnerID=8YFLogxK
U2 - 10.1146/annurev-arplant-050718-100231
DO - 10.1146/annurev-arplant-050718-100231
M3 - Review article
C2 - 31035831
AN - SCOPUS:85065056884
SN - 1543-5008
VL - 70
SP - 213
EP - 238
JO - Annual Review of Plant Biology
JF - Annual Review of Plant Biology
ER -