Heterogeneity moderates treatment response among patients with binge eating disorder

Robyn Sysko, Tom Hildebrandt, G. Terence Wilson, Denise E. Wilfley, W. Stewart Agras

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Objective: The purpose of the study was to explore heterogeneity and differential treatment outcome among a sample of patients with binge eating disorder (BED). Method: A latent class analysis was conducted with 205 treatment-seeking, overweight or obese individuals with BED randomized to interpersonal psychotherapy (IPT), behavioral weight loss (BWL), or guided self-help based on cognitive behavioral therapy (CBTgsh). A latent transition analysis tested the predictive validity of the latent class analysis model. Results: A 4-class model yielded the best overall fit to the data. Class 1 was characterized by a lower mean body mass index (BMI) and increased physical activity. Individuals in Class 2 reported the most binge eating, shape and weight concerns, compensatory behaviors, and negative affect. Class 3 patients reported similar binge eating frequencies to Class 2, with lower levels of exercise or compensation. Class 4 was characterized by the highest average BMI, the most overeating episodes, fewer binge episodes, and an absence of compensatory behaviors. Classes 1 and 3 had the highest and lowest percentage of individuals with a past eating disorder diagnosis, respectively. The latent transition analysis found a higher probability of remission from binge eating among those receiving IPT in Class 2 and CBTgsh in Class 3. Conclusions: The latent class analysis identified 4 distinct classes using baseline measures of eating disorder and depressive symptoms, body weight, and physical activity. Implications of the observed differential treatment response are discussed.

Original languageEnglish
Pages (from-to)681-690
Number of pages10
JournalJournal of Consulting and Clinical Psychology
Volume78
Issue number5
DOIs
StatePublished - Oct 1 2010

Keywords

  • binge eating disorder
  • latent class analysis
  • latent transition analysis
  • treatment specificity

Fingerprint Dive into the research topics of 'Heterogeneity moderates treatment response among patients with binge eating disorder'. Together they form a unique fingerprint.

  • Cite this