Herpetic Panophthalmitis: A Diagnostic Dilemma

L. M. Hassman, M. M. Chung, M. Gonzalez, A. P. Bessette

Research output: Contribution to journalLetterpeer-review


Purpose: To describe an uncommon presentation of ocular infection caused by human herpes simplex virus 2 (HSV-2). Methods: Case report. Results: A 32-year-old female with no prior history of mucocutaneous herpesvirus infection presented with a minimally painful hypertensive granulomatous panophthalmitis and optic neuropathy that was initially suspected to be orbital cellulitis. Her disease progressed despite antibiotic and steroid treatment, and HSV-2 was ultimately identified in the vitreous. Conclusion: Although rare, ocular infection by human herpesvirus can present as a panophthalmitis. The case is discussed in the context of two previously reported cases of herpes simplex panophthalmitis, as well panophthalmitis caused by varicella zoster virus.

Original languageEnglish
Pages (from-to)116-118
Number of pages3
JournalOcular Immunology and Inflammation
Issue number1
StatePublished - Jan 2 2020


  • Acute retinal necrosis
  • HSV-2
  • Panophthalmitis


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