TY - JOUR
T1 - Herpes simplex virus keratitis among patients who are positive or negative for human immunodeficiency virus
T2 - An epidemiologic study
AU - Hodge, W. G.
AU - Margolis, T. P.
N1 - Funding Information:
Supported in part by a Research to Prevent Blindness (New York, NY) career development award (Dr. Margolis) and the McLaughlin Foundation of Canada (Toronto, Canada) (Dr. Hodge). Each author states that he has no proprietary interest in the development or marketing of any product or service mentioned in the article. Reprint requests to Todd Margolis, MD, PhD, Francis l. Proctor Foundation, 95 Kirkham Street, San Francisco, CA 94122.
PY - 1997
Y1 - 1997
N2 - Purpose: The authors compare the incidence and clinical course of herpes simplex virus (HSV) keratitis among patients who are positive and negative for human immunodeficiency virus (HIV). Methods: A retrospective cohort study was designed. Outcomes measured in both groups included incidence of HSV keratitis, lesion type (epithelial vs. stromal), lesion location (central vs. peripheral), treatment time, time to first recurrence, and recurrence rate. Results: There was no statistically significant difference between the groups for any of the outcomes measured except for recurrence rate. The recurrence rate was 2.48 times more frequent among patients positive for HIV (1 recurrence per 587 person-days of follow-up among patients positive for HIV vs. 1 per 1455 person-days among patients negative for HIV). Conclusions: Except for recurrence rate, the incidence and clinical course of HSV keratitis in this study were no different among patients positive and negative for HIV.
AB - Purpose: The authors compare the incidence and clinical course of herpes simplex virus (HSV) keratitis among patients who are positive and negative for human immunodeficiency virus (HIV). Methods: A retrospective cohort study was designed. Outcomes measured in both groups included incidence of HSV keratitis, lesion type (epithelial vs. stromal), lesion location (central vs. peripheral), treatment time, time to first recurrence, and recurrence rate. Results: There was no statistically significant difference between the groups for any of the outcomes measured except for recurrence rate. The recurrence rate was 2.48 times more frequent among patients positive for HIV (1 recurrence per 587 person-days of follow-up among patients positive for HIV vs. 1 per 1455 person-days among patients negative for HIV). Conclusions: Except for recurrence rate, the incidence and clinical course of HSV keratitis in this study were no different among patients positive and negative for HIV.
UR - http://www.scopus.com/inward/record.url?scp=0031045017&partnerID=8YFLogxK
U2 - 10.1016/S0161-6420(97)30351-0
DO - 10.1016/S0161-6420(97)30351-0
M3 - Article
C2 - 9022115
AN - SCOPUS:0031045017
SN - 0161-6420
VL - 104
SP - 120
EP - 124
JO - Ophthalmology
JF - Ophthalmology
IS - 1
ER -