Hereditary alpha-tryptasemia modifies clinical phenotypes among individuals with congenital hypermobility disorders

Medicine and Dentistry

• Disease 100%
• Autosomal Dominant Inheritance 66%
• Tryptase 66%
• Prevalence 33%
• Clinical Feature 33%
• Plummer-Vinson Syndrome 33%
• Pruritus 33%
• Skeleton Malformation 33%
• Spectrum Disorder 33%
• Anaphylaxis 33%
• Ehlers Danlos Syndrome 33%
• Endotype 33%
• Joint Laxity 33%
• Genetic Trait 33%
• Primary Dentition 33%

Keyphrases

• Clinical Phenotype 100%
• Hypermobility 100%
• Hereditary alpha-tryptasemia 100%
• Autosomal Dominant 28%
• Tryptase 14%
• Skeletal Abnormalities 14%
• Clinical Features 14%
• Clinical Presentation 14%
• Copy number 14%
• Pruritus 14%
• Limited Samples 14%
• Dysphagia 14%
• Complex Patients 14%
• Anaphylaxis 14%
• Genetic Etiology 14%
• Western Population 14%
• Genetic Traits 14%
• Joint Hypermobility 14%
• Combined Cohort 14%
• Hypermobile Ehlers-Danlos Syndrome 14%
• TPSAB1 14%
• Primary Dentition 14%
• Basal Serum Tryptase 14%

Biochemistry, Genetics and Molecular Biology

• Autosomal Dominant Inheritance 100%
• Tryptase 100%
• Genetics 50%
• Prevalence 50%
• Genetic Trait 50%
• Genotyping 50%
• Sample Size 50%