HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium

Keyphrases

• Intestinal Epithelium 100%
• Hyperplasia 100%
• Crypt 100%
• HER2 mutation 100%
• APC mutation 100%
• Villus Morphology 100%
• TGR5 40%
• Recurrent mutation 20%
• Cell Proliferation 20%
• Cre Recombinase 20%
• Cell Differentiation 20%
• Transgenic Mice 20%
• Human Epidermal Growth Factor Receptor 2 (HER2) 20%
• Cancer Genome Atlas 20%
• Gene mutation 20%
• Mouse Intestine 20%
• Epithelium 20%
• Secretory Cells 20%
• Genome Editing 20%
• Villi 20%
• Colon Cancer 20%
• Transmission Electron Microscopy 20%
• Colon Cancer Patients 20%
• Small Colon 20%
• Colorectal Cancer Patients 20%
• Organoids 20%
• Activating mutation 20%
• Intestinal Villi 20%
• Tg Mouse 20%
• Intestinal Crypts 20%
• Villin-Cre 20%
• Intermediate Cell 20%
• HER2 Amplification 20%
• MUC2 20%
• Matrix Metalloproteinase 7 (MMP7) 20%
• TALEN 20%
• Intrinsic Roles 20%
• ApcMin 20%
• Secretory Expression 20%
• Gene Expression Assay 20%
• Intestinal Stem Cell Marker 20%
• Co-immunofluorescence 20%
• Crypt Formation 20%
• Co-transmission 20%

Medicine and Dentistry

• APC 100%
• Intestinal Epithelium 100%
• Hyperplasia 100%
• Crypt 100%
• Colon Carcinoma 40%
• Gene Expression Profiling 20%
• Cell Proliferation 20%
• Cell Differentiation 20%
• Morphology 20%
• Small Intestine 20%
• Transgene 20%
• Cre Recombinase 20%
• Transgenic Mouse 20%
• Immunofluorescence 20%
• Colon 20%
• The Cancer Genome Atlas 20%
• Transmission Electron Microscopy 20%
• Organoid 20%
• Cell Marker 20%
• Colorectal Carcinoma 20%
• Intestinal Stem Cell 20%
• Villin 20%
• Secretory Cell 20%
• Mucin 2 20%
• Matrilysin 20%
• Transcription Activator Like Effector 20%
• Intestinal Villus 20%
• Epithelium 20%

Immunology and Microbiology

• Antigen-Presenting Cell 100%
• Epithelium 100%
• Colon 60%
• Cell Differentiation 20%
• Transgenic Mouse 20%
• Transgene 20%
• Organoid 20%
• Immunofluorescence 20%
• Lineages 20%
• Cell Proliferation 20%
• Morphology 20%
• Small Intestine 20%
• Intestinal Stem Cell 20%
• Gene Editing 20%
• Cell Marker 20%
• Intestine Villus 20%
• Secretory Cell 20%
• Transmission Electron Microscopy 20%
• MUC2 20%
• Transcription Activator Like Effector 20%
• Gene Expression Assay 20%
• Colorectal Carcinoma 20%