TY - JOUR
T1 - Hepatic hemangiomas and malignant tumors
T2 - Improved differentiation with heavily T2-weighted conventional spin-echo MR imaging
AU - McFarland, Elizabeth G.
AU - Mayo-Smith, William W.
AU - Saini, Sanjay
AU - Hahn, Peter F.
AU - Goldberg, Mark A.
AU - Lee, Michael J.
PY - 1994/10
Y1 - 1994/10
N2 - PURPOSE: To determine whether hemangiomas and malignant tumors can be better differentiated at 1.5-T magnetic resonance imaging with use of more heavily T2-weighted conventional spin-echo sequences. MATERIALS AND METHODS: Eighty-three patients with focal liver lesions (50 malignant tumors, 24 hemangiomas, nine cysts) larger than 1 cm were studied with a 3,000/80, 160 sequence (repetition time msec/echo time [TE] msec). T2 relaxation times and lesion/liver signal intensity ratios at TEs of 80 and 160 msec were measured. Receiver operating characteristic (ROC) analyses of expert readers and quantitative measures were performed. RESULTS: T2 relaxation times demonstrated the best performance in distinguishing hemangiomas from malignant tumors (area under ROC curve = .99 ± .01). Mean T2 times were 76 msec ± 11 for malignant tumors, 142 msec ± 40 for hemangiomas, and 341 msec ± 38 for cysts. A cutoff T2 value of 112 msec allowed discrimination between hemangiomas and malignant tumors with a 97% accuracy, 100% sensitivity, and 92% specificity. CONCLUSION: Hemangiomas and malignant tumors are better differentiated with use of T2 relaxation times obtained with a more heavily T2-weighted sequence.
AB - PURPOSE: To determine whether hemangiomas and malignant tumors can be better differentiated at 1.5-T magnetic resonance imaging with use of more heavily T2-weighted conventional spin-echo sequences. MATERIALS AND METHODS: Eighty-three patients with focal liver lesions (50 malignant tumors, 24 hemangiomas, nine cysts) larger than 1 cm were studied with a 3,000/80, 160 sequence (repetition time msec/echo time [TE] msec). T2 relaxation times and lesion/liver signal intensity ratios at TEs of 80 and 160 msec were measured. Receiver operating characteristic (ROC) analyses of expert readers and quantitative measures were performed. RESULTS: T2 relaxation times demonstrated the best performance in distinguishing hemangiomas from malignant tumors (area under ROC curve = .99 ± .01). Mean T2 times were 76 msec ± 11 for malignant tumors, 142 msec ± 40 for hemangiomas, and 341 msec ± 38 for cysts. A cutoff T2 value of 112 msec allowed discrimination between hemangiomas and malignant tumors with a 97% accuracy, 100% sensitivity, and 92% specificity. CONCLUSION: Hemangiomas and malignant tumors are better differentiated with use of T2 relaxation times obtained with a more heavily T2-weighted sequence.
KW - Angioma, gastrointestinal tract
KW - Liver neoplasms, MR
UR - http://www.scopus.com/inward/record.url?scp=0028136485&partnerID=8YFLogxK
U2 - 10.1148/radiology.193.1.8090920
DO - 10.1148/radiology.193.1.8090920
M3 - Article
C2 - 8090920
AN - SCOPUS:0028136485
SN - 0033-8419
VL - 193
SP - 43
EP - 47
JO - Radiology
JF - Radiology
IS - 1
ER -