Hemodynamic studies of platelet thrombosis using microfluidics

Susan M. Hastings, Michael T. Griffin, David N. Ku

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations

Abstract

Platelets contribute to thrombus formation in a variety of ways. Platelet adhesion, activation, and thrombus growth depend greatly on the type of hemodynamic environment surrounding an inciting event. Microfluidic systems may be used to explore these relationships. In this review, we describe some important considerations required in the design of a microfluidic system and identify some limitations that may require use of a macroscale system.

Original languageEnglish
Pages (from-to)427-433
Number of pages7
JournalPlatelets
Volume28
Issue number5
DOIs
StatePublished - Jul 4 2017

Keywords

  • microfluidics
  • platelets
  • thrombosis

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