Hemodynamic effects of new intra-aortic balloon counterpulsation timing methods in patients: A multicenter evaluation

Morton J. Kern, Frank V. Aguirre, Eugene A. Caracciolo, Richard G. Bach, Thomas J. Donohue, David Lasorda, E. Magnus Ohman, Robert N. Schnitzler, Donald L. King, William J. Ohley, Joseph Grayzel

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Abstract

Background: To test whether later intra-aortic balloon pump (IABP) deflation approaching or simultaneous with left ventricular ejection would improve hemodynamics and myocardial efficiency with the use of new balloon deflation methods, 4 IABP timing techniques were evaluated in 43 patients. Methods and Results: Later balloon deflation produced significantly greater percentage changes in mean aortic pressure (6% vs 1%), systolic pressure time index (-27% vs -20%), diastolic pressure time index (35% vs 19%), and the systolic pressure-time index/diastolic pressure-time index ratio (97% vs 51%), respectively. However, these changes increased peak systolic pressure (-15% vs -11%). Cardiac output and stroke volume indexes were not significantly altered over the 4 settings. Conclusions: These data suggest that systemic hemodynamics and myocardial efficiency may be improved by later balloon deflation approaching left ventricular ejection in comparison to conventional IABP timing.

Original languageEnglish
Pages (from-to)1129-1136
Number of pages8
JournalAmerican heart journal
Volume137
Issue number6
DOIs
StatePublished - Jan 1 1999
Externally publishedYes

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    Kern, M. J., Aguirre, F. V., Caracciolo, E. A., Bach, R. G., Donohue, T. J., Lasorda, D., Ohman, E. M., Schnitzler, R. N., King, D. L., Ohley, W. J., & Grayzel, J. (1999). Hemodynamic effects of new intra-aortic balloon counterpulsation timing methods in patients: A multicenter evaluation. American heart journal, 137(6), 1129-1136. https://doi.org/10.1016/S0002-8703(99)70373-X