Hemodynamic-directed cardiopulmonary resuscitation during in-hospital cardiac arrest

Robert M. Sutton, Stuart H. Friess, Matthew R. Maltese, Maryam Y. Naim, George Bratinov, Theodore R. Weiland, Mia Garuccio, Utpal Bhalala, Vinay M. Nadkarni, Lance B. Becker, Robert A. Berg

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


Cardiopulmonary resuscitation (CPR) guidelines assume that cardiac arrest victims can be treated with a uniform chest compression (CC) depth and a standardized interval administration of vasopressor drugs. This non-personalized approach does not incorporate a patient's individualized response into ongoing resuscitative efforts. In previously reported porcine models of hypoxic and normoxic ventricular fibrillation (VF), a hemodynamic-directed resuscitation improved short-term survival compared to current practice guidelines. Skilled in-hospital rescuers should be trained to tailor resuscitation efforts to the individual patient's physiology. Such a strategy would be a major paradigm shift in the treatment of in-hospital cardiac arrest victims.

Original languageEnglish
Pages (from-to)983-986
Number of pages4
Issue number8
StatePublished - Aug 2014


  • Arterial blood pressure
  • Cardiac arrest
  • Cardiopulmonary resuscitation


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