Hemodynamic Complications of Ventricular Septal Rupture after Acute Myocardial Infarction

Brett M. Sasseen, Osvaldo S. Gigliotti, Steven Lavine, Paul S. Gilmore, Robert Percy, Theodore A. Bass

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Ventricular septal rupture (VSR) is a rare but serious complication following acute myocardial infarction (MI). Patients may present with a new murmur associated with a thrill. Right heart catheterization will demonstrate elevated right atrial and pulmonary artery pressures as well as an oxygen step-up at the right ventricular level. Patients with a right ventricular infarction or cardiogenic shock and a ventricular septal rupture have high in-hospital mortality rates. Prompt diagnosis followed by surgical repair is essential for patients with VSR following MI.

Original languageEnglish
Pages (from-to)509-514
Number of pages6
JournalCatheterization and Cardiovascular Interventions
Issue number4
StatePublished - Dec 1 2003


  • Cardiogenic shock
  • Mitral regurgitation
  • Ventricular septal defect


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