Hematopoietic Cell Transplantation, Version 3.2022 Featured Updates to the NCCN Guidelines

  • Ayman Saad
  • , Alison Loren
  • , Javier Bolaños-Meade
  • , George Chen
  • , Daniel Couriel
  • , Antonio Di Stasi
  • , Areej El-Jawahri
  • , Hany Elmariah
  • , Sherif Farag
  • , Krishna Gundabolu
  • , Jonathan Gutman
  • , Vincent Ho
  • , Rasmus Hoeg
  • , Mitchell Horwitz
  • , Joe Hsu
  • , Adetola Kassim
  • , Mohamed Kharfan Dabaja
  • , John Magenau
  • , Thomas Martin
  • , Marco Mielcarek
  • Jonathan Moreira, Ryotaro Nakamura, Yago Nieto, Cameron Ninos, Caspian Oliai, Seema Patel, Brion Randolph, Mark Schroeder, Dimitrios Tzachanis, Asya Nina Varshavsky-Yanovsky, Madhuri Vusirikala, Frankie Algieri, Lenora A. Pluchino

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The NCCN Guidelines for Hematopoietic Cell Transplantation (HCT) provide an evidence- and consensus-based approach for the use of autologous and allogeneic HCT in the management of malignant diseases in adult patients. HCT is a potentially curative treatment option for patients with certain types of malignancies; however, recurrent malignancy and transplant-related complications often limit the long-term survival of HCT recipients. The purpose of these guidelines is to provide guidance regarding aspects of HCT, including pretransplant recipient evaluation, hematopoietic cell mobilization, and treatment of graft-versus-host disease—a major complication of allogeneic HCT—to enable the patient and clinician to assess management options in the context of an individual patient’s condition. These NCCN Guidelines Insights provide a summary of the important recent updates to the NCCN Guidelines for HCT, including the incorporation of a newly developed section on the Principles of Conditioning for HCT.

Original languageEnglish
Pages (from-to)108-115
Number of pages8
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume21
Issue number2
DOIs
StatePublished - Feb 2023

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