Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus

Irene Ramos; Mena Mansour; Teddy J. Wohlbold; Megan E. Ermler; Ariana Hirsh; Jonathan A. Runstadler; Ana Fernandez-Sesma; Florian Krammer

doi:10.3201/eid2107.141755

Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus

Irene Ramos, Mena Mansour, Teddy J. Wohlbold, Megan E. Ermler, Ariana Hirsh, Jonathan A. Runstadler, Ana Fernandez-Sesma, Florian Krammer

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.

Original language	English
Pages (from-to)	1197-1201
Number of pages	5
Journal	Emerging Infectious Diseases
Volume	21
Issue number	7
DOIs	https://doi.org/10.3201/eid2107.141755
State	Published - 2015

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title = "Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus",

abstract = "Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.",

author = "Irene Ramos and Mena Mansour and Wohlbold, {Teddy J.} and Ermler, {Megan E.} and Ariana Hirsh and Runstadler, {Jonathan A.} and Ana Fernandez-Sesma and Florian Krammer",

year = "2015",

doi = "10.3201/eid2107.141755",

language = "English",

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AU - Ramos, Irene

AU - Mansour, Mena

AU - Wohlbold, Teddy J.

AU - Ermler, Megan E.

AU - Hirsh, Ariana

AU - Runstadler, Jonathan A.

AU - Fernandez-Sesma, Ana

AU - Krammer, Florian

PY - 2015

Y1 - 2015

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AB - Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.

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U2 - 10.3201/eid2107.141755

DO - 10.3201/eid2107.141755

M3 - Article

C2 - 26079843

AN - SCOPUS:84931365600

SN - 1080-6040

VL - 21

SP - 1197

EP - 1201

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 7

ER -

Hemagglutinin receptor binding of a human isolate of influenza A(H10N8) virus

Abstract

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