Heart transplantation in pediatric cardiomyopathies

Brian F. Birnbaum, Kathleen E. Simpson, Charles E. Canter

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


Cardiomyopathies represent an uncommon but serious cause of heart disease in the pediatric population and can be categorized as dilated, hypertrophic, restrictive and left ventricular non-compaction. Each of these subtypes has multiple potential genetic etiologies in addition to possible non-genetic causes. Many patients with cardiomyopathies can benefit from transplantation, although there is not insignificant morbidity and mortality for those patients. Outcomes both prior to and following transplantation depend on the underlying etiology, the amount of support needed prior to transplantation and the illness severity of the patient prior to transplantation. Mechanical circulatory support is frequently used to bridge patients to transplantation, and newer technologies are currently in development.

Original languageEnglish
Pages (from-to)1677-1690
Number of pages14
JournalExpert Review of Cardiovascular Therapy
Issue number12
StatePublished - Nov 26 2013


  • Dilated cardiomyopathy
  • Heart failure
  • Heart transplantation
  • Hypertrophic cardiomyopathy
  • Mechanical circulatory support
  • Pediatrics


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