Heart rate variability: Measurement and clinical utility

Research output: Contribution to journalReview article

615 Scopus citations

Abstract

Electrocardiographic RR intervals fluctuate cyclically, modulated by ventilation, baroreflexes, and other genetic and environmental factors that are mediated through the autonomic nervous system. Short term electrocardiographic recordings (5 to 15 minutes), made under controlled conditions, e.g., lying supine or standing or tilted upright can elucidate physiologic, pharmacologic, or pathologic changes in autonomic nervous system function. Long-term, usually 24-hour recordings, can be used to assess autonomic nervous responses during normal daily activities in health, disease, and in response to therapeutic interventions, e.g., exercise or drugs. RR interval variability is useful for assessing risk of cardiovascular death or arrhythmic events, especially when combined with other tests, e.g., left ventricular ejection fraction or ventricular arrhythmias.

Original languageEnglish
Pages (from-to)88-101
Number of pages14
JournalAnnals of Noninvasive Electrocardiology
Volume10
Issue number1
DOIs
StatePublished - Jan 1 2005

Keywords

  • Autonomic nervous system

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