TY - JOUR
T1 - Head and neck squamous cell carcinoma and its correlation with human papillomavirus in people living with HIV
T2 - A systematic review
AU - Ceccarelli, Manuela
AU - Rullo, Emmanuele Venanzi
AU - Facciolà, Alessio
AU - Madeddu, Giordano
AU - Cacopardo, Bruno
AU - Taibi, Rosaria
AU - D'Aleo, Francesco
AU - Pinzone, Marilia Rita
AU - Picerno, Isa
AU - Rosa, Michele di
AU - Visalli, Giuseppa
AU - Condorelli, Fabrizio
AU - Nunnari, Giuseppe
AU - Pellicanò, Giovanni Francesco
N1 - Publisher Copyright:
© Ceccarelli et al.
PY - 2018/3/30
Y1 - 2018/3/30
N2 - Over the last 20 years we assisted to an increase in the mean age of People Living with HIV and their comorbidities. Especially, there was an increase in Human Papillomavirus-related head and neck squamous cell carcinomas. Despite their increasing incidence in HIV-positive people, mechanisms that lead to their development and progression are only partially understood. The aim of this review is to identify key data and factors about HPV-related head and neck squamous cell carcinoma in HIV-seropositive patients. Systematic search and review of the relevant literature-peer-reviewed and grey-was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. We included in our review only the 35 full-text articles we considered the most substantial. It is mandatory to improve our knowledge about the interactions existing between HPV and HIV, and about their actions on oral mucosa immune system.
AB - Over the last 20 years we assisted to an increase in the mean age of People Living with HIV and their comorbidities. Especially, there was an increase in Human Papillomavirus-related head and neck squamous cell carcinomas. Despite their increasing incidence in HIV-positive people, mechanisms that lead to their development and progression are only partially understood. The aim of this review is to identify key data and factors about HPV-related head and neck squamous cell carcinoma in HIV-seropositive patients. Systematic search and review of the relevant literature-peer-reviewed and grey-was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. We included in our review only the 35 full-text articles we considered the most substantial. It is mandatory to improve our knowledge about the interactions existing between HPV and HIV, and about their actions on oral mucosa immune system.
KW - Head and neck cancer
KW - HIV
KW - HNSCC
KW - HPV
KW - Papillomavirus
UR - http://www.scopus.com/inward/record.url?scp=85044792151&partnerID=8YFLogxK
U2 - 10.18632/oncotarget.24660
DO - 10.18632/oncotarget.24660
M3 - Review article
C2 - 29682214
AN - SCOPUS:85044792151
SN - 1949-2553
VL - 9
SP - 17171
EP - 17180
JO - Oncotarget
JF - Oncotarget
IS - 24
ER -