Harnessing human dendritic cell subsets to design novel vaccines

Jacques Banchereau; Eynav Klechevsky; Nathalie Schmitt; Rimpei Morita; Karolina Palucka; Hideki Ueno

doi:10.1111/j.1749-6632.2009.04999.x

Harnessing human dendritic cell subsets to design novel vaccines

Jacques Banchereau, Eynav Klechevsky, Nathalie Schmitt, Rimpei Morita, Karolina Palucka, Hideki Ueno

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

Dendritic cells (DCs) orchestrate a repertoire of immune responses that endow resistance to infection and tolerance to self. DC plasticity and subsets are prominent determinants of the quality of elicited immune responses. Different DC subsets display different receptors and surface molecules and express different sets of cytokines/chemokines, all of which lead to distinct immunological outcomes. Recent findings on human DC subsets and their functional specialization have provided insights for the design of novel human vaccines.

Original language	English
Pages (from-to)	24-32
Number of pages	9
Journal	Annals of the New York Academy of Sciences
Volume	1174
DOIs	https://doi.org/10.1111/j.1749-6632.2009.04999.x
State	Published - 2009

Keywords

Dendritic cell
Immunology
Vaccine

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10.1111/j.1749-6632.2009.04999.x

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AU - Palucka, Karolina

AU - Ueno, Hideki

PY - 2009

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KW - Dendritic cell

KW - Immunology

KW - Vaccine

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JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

ER -

Harnessing human dendritic cell subsets to design novel vaccines

Abstract

Keywords

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